Ski-1/s1p facilitates sars-cov-2 spike induced cell-to-cell fusion via activation of srebp-2 and metalloproteases, whereas pcsk9 enhances the degradation of ace2

HIGHLIGHTS

• who: Rachid Essalmani et al. from the Laboratory of Biochemical Neuroendocrinology, Montreal Clinical Research Institute (IRCM), Universitu00e9 de Montru00e9al, Montreal, QC H W , Canada have published the research work: SKI-1/S1P Facilitates SARS-CoV-2 Spike Induced Cell-to-Cell Fusion via Activation of SREBP-2 and Metalloproteases, Whereas PCSK9 Enhances the Degradation of ACE2, in the Journal: Viruses 2023, 15, 360. of 25/01/2023
• what: The authors recently showed that the convertase furin is critical for the infectivity of SARS-CoV-2 which requires cleavage of its spike protein (S) at two . . .
  

   

  

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