Vascular refilling coefficient is not a good marker of whole-body capillary hydraulic conductivity in hemodialysis patients: insights from a simulation study

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SUMMARY

    The hydrostatic pressure of the interstitial fluid was described as a linear function of the interstitial v­ olume24: Pis=Pis,n + · Vis - Vis,n Cis where ­Pis,n is the normal interstitial pressure (assumed at -1 ­mmHg32) corresponding to the normal interstitial volume ­(Vis,n, assumed 15 ­L24,33) and ­Cis is the interstitial compliance, which was assumed to be 12% of normal interstitial volume per mm ­Hg32. This can be explained by the fact that, contrary to the assumption by Tabei et_al11,12, during HD it is not only plasma oncotic pressure that . . .

     

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