HIGHLIGHTS
- who: Yin Luo from the DepartmentUniversity at have published the research work: Biochemical characterization of a disease-causing human osteoprotegerin variant, in the Journal: Scientific Reports Scientific Reports
- what: By using primary murine articular chondrocytes (Fig 5A, B shown chondrocytes actively secrete type-II collagen), the authors show that TRAIL dose-dependently induced apoptosis of articular chondrocytes (Fig 5C-F and I). All animal works in this study have been approved by the institutional animal care and use committee of the University at Buffalo (protocol number: ORB14126N), and the study is reported in accordance with . . .
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