Pdia4, a new endoplasmic reticulum stress protein, modulates insulin resistance and inflammation in skeletal muscle

HIGHLIGHTS

  • who: Chien-Hsing Lee and collaborators from the Tongji University, China have published the research work: PDIA4, a new endoplasmic reticulum stress protein, modulates insulin resistance and inflammation in skeletal muscle, in the Journal: (JOURNAL)
  • what: The authors first explored whether ER stressinduced PDIA4 was involved in skeletal muscle IR. The Internal Review Board of the Ethics Committee of the Tri-Service General Hospital approved this study (institutional review board approval number: 098-05-182), and all enrolled subjects provided written informed consent. The study showed that palmitate and insulin increased PDIA4, inflammatory cytokines, and . . .

     

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