Targeting fibrosis: mechanisms and clinical trials

HIGHLIGHTS

  • who: Manyu Zhao from the (UNIVERSITY) have published the Article: Targeting fibrosis: mechanisms and clinical trials, in the Journal: (JOURNAL) of 17/06/2022
  • what: The high mortality and complex pathogenesis of fibrotic diseases pose great challenges in clinical therapy.
  • how: The previous results showed that GFT505 could inhibit steatosis inflammation and fibrosis in a NASH mouse model and reduce the expression of lipid metabolism- inflammation- and fibrosis-related signaling molecules323. Showed that most biomarkers of lipid inflammation and fibrosis were improved in both dose groups of lanifibranor.
  • future: Studies have . . .

     

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