Oncogene convergence extrachromosomal associated with worse clinical outcomes compared with other types of oncogene amplification

HIGHLIGHTS

• who: VIEWS and collaborators from the Center for PersonalStanford University have published the research work: Oncogene Convergence Extrachromosomal associated with worse clinical outcomes compared with other types of oncogene amplification, in the Journal: (JOURNAL) of 21/02/2023

SUMMARY

Published by the American Association for Cancer Research ecDNAs include paired chromatin bodies termed double minutes (DM), first described in the 1960s, although the authors now know that only a subset of ecDNAs are detectable as double minutes on chromosome spreads. Compared with cancers containing chromosomal oncogene amplifications, ecDNA-containing tumors are associated with . . .

 



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