Impaired antigen-specific b-cell responses after influenza vaccination in kidney transplant recipients receiving co-stimulation blockade with belatacept

HIGHLIGHTS

  • who: Vincent Pernin and colleagues from the The University of Melbourne, Australia have published the article: Impaired antigen-specific B-cell responses after Influenza vaccination in kidney transplant recipients receiving co-stimulation blockade with Belatacept, in the Journal: (JOURNAL)
  • what: The authors investigated the dynamics of Tfh and antigen-specific antibody responses by hemagglutination inhibition test and B-cell immune_responses in belatacepttreated kidney transplant patients compared to standard of care Tacrolimus (Tac)-treated patients, after receiving a T-cell dependent booster vaccination against Influenza virus. When the authors focused on activated CD4+CD45RA-CXCR5+ ICOS . . .

     

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