The runx family defines trk phenotype and aggressiveness of human neuroblastoma through regulation of p53 and mycn

HIGHLIGHTS

• who: Kiyohiro Ando and Akira Nakagawara from the Research Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan have published the research work: The RUNX Family Defines Trk Phenotype and Aggressiveness of Human Neuroblastoma through Regulation of p53 and MYCN, in the Journal: Cells 2023, 544 of /2023/
• what: Accelerated proliferation induced by an oncogene requires, at least in part, a safeguarding mechanism to prevent deleterious consequences such as mitotic catastrophe [101].

SUMMARY

The Runt-related transcription factor (RUNX) family, which has essential roles in neural development and differentiation through regulation . . .

 



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