Combpdx: a unified statistical framework for evaluating drug synergism in patient-derived xenografts

HIGHLIGHTS

  • who: Licai Huang from the DepartmentThe University have published the article: CombPDX: a unified statistical framework for evaluating drug synergism in patient-derived xenografts, in the Journal: Scientific Reports Scientific Reports
  • what: At each time point, the authors determine the treatment effects of A, B, and AB compared to the control group C (Fig 1c). Based on the treatment effects, the authors provide the CIs under HSA, RA, and BI, and the corresponding 95% confidence intervals (Fig 1d). The authors develop statistical inferential procedures by deriving confidence intervals for the CIs under the asymptotic normality . . .

     

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