HIGHLIGHTS
- who: Anastasija Panevska from the DepartmentUniversity of have published the research work: A single point mutation expands the applicability of ostreolysin A6 in biomedicine, in the Journal: Scientific Reports Scientific Reports
- what: Our combined results confirm that the single point mutation of glutamic acid at position 69 to alanine indeed greatly improves the interaction of OlyA6 with both mammalian- and invertebrate-principal membrane sphingolipid species, the sphingomyelin and the CPE.
SUMMARY
The membrane interaction of E69A was considerably stronger in the presence of PlyB, suggesting the formation of bi-component protein . . .
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