The essential roles of fxr in diet and age influenced metabolic changes and liver disease development: a multi-omics study

HIGHLIGHTS

• who: Guiyan Yang from the Department of Pathology and Laboratory Medicine, University Ave, Sacramento, CA, USA have published the article: The essential roles of FXR in diet and age influenced metabolic changes and liver disease development: a multi-omics study, in the Journal: (JOURNAL)
• what: This study investigated the impact of WD intake and aging on metabolic liver disease development in WT and FXR KO mice based on multi-omics data.

SUMMARY

WD‑altered hepatic transcripts and pathways were largely dependent on FXR function Principal component analysis (PCA) of hepatic transcriptomes . . .

 



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