HIGHLIGHTS
- who: Jung-Soo Suh from the (UNIVERSITY) have published the article: A novel DNA double-strand breaks biosensor based on fluorescence resonance energy transfer, in the Journal: (JOURNAL)
- what: By applying FRET imaging with DSBS the authors show that DSBS specifically reacts to drug- or ionizing radiation (IR)-induced u03b3H2AX activity allowing for the quantification of DSB events at high spatiotemporal resolutions. Taken together the authors provide new experimental tool to evaluate the spatiotemporal dynamics of double-strand Ultimately the biosensor can be useful for elucidating the molecular mechanisms underlying damage and repair processes. To . . .
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