Glutamine is a substrate for glycosylation and ca19-9 biosynthesis through hexosamine biosynthetic pathway in pancreatic cancer

HIGHLIGHTS

  • who: Chen Liu from the College, Fudan University, Shanghai, China Pancreatic Cancer Institute, Fudan University, Shanghai, China Shanghai have published the article: Glutamine is a substrate for glycosylation and CA19-9 biosynthesis through hexosamine biosynthetic pathway in pancreatic cancer, in the Journal: (JOURNAL)
  • what: In this study, the proliferation of pancreatic cancer cells (SW1990, BxPC-3, and SU.8686) at different time points with and without 2 mM glutamine was determined by CCK-8 and colony formation assays. Since the type I chain (Gal-GlcNAc) is the backbone structure of CA19-9 , the authors propose . . .

     

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