Altered lipid metabolites accelerate early dysfunction of t cells in hiv-infected rapid progressors by impairing mitochondrial function

HIGHLIGHTS

  • who: Si-Yao Li and colleagues from the Ben-Gurion University of the Negev, Israel Tulane University, United States have published the Article: Altered lipid metabolites accelerate early dysfunction of T cells in HIV-infected rapid progressors by impairing mitochondrial function, in the Journal: (JOURNAL)
  • what: In the present study, an 11-lipid metabolite signature was identified that could predict rapid disease progression at ~120 days of infection with an accuracy of 91.9%, as measured by AUC. The study demonstrated that rapid HIV disease progression could be predicted by the profile of 11 lipid . . .

     

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