Exercise as an aging mimetic: a new perspective on the mechanisms behind exercise as preventive medicine against age-related chronic disease

HIGHLIGHTS

SUMMARY

    Age-related chronic diseases (e_g, cardiovascular disease, chronic kidney disease, Alzheimer`s Dementia, Type II Diabetes, etc.) are among the most common causes of mortality and account for a majority of global disease burden (Yach et_al, 2004; Kennedy et_al, 2014; Murphy et_al, 2018). Preventive lifestyle strategies such as exercise have emerged as potent, cost-effective means of reducing chronic disease risk (Sallis, 2009; Sepanlou et_al, 2011; Bauer et_al, 2014). Agerelated increases in blood pressure may stem from, and simultaneously promote, large artery stiffening (Henskens et_al, 2008; Najjar et_al, 2008; Kaess et_al, 2012; Mitchell, 2014 . . .

     

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