HIGHLIGHTS
- who: Weerayut Wongjampa et al. from the Faculty of Medicine, Department of Microbiology, Khon Kaen University, Khon Kaen, Thailand, HPV and have published the article: An in vitro carcinogenesis model for cervical cancer harboring episomal form of HPV16, in the Journal: PLOS ONE of January/14,/2023
- what: The authors investigated the tumorigenic potential of human cervical keratinocytes harboring only the episomal form of HPV16 (HCK1T/16epi). As the authors reported that expression of HPV16 E6E7 and KRASG12V was sufficient to induce tumorigenicity of primary HCK cells, and the major signaling pathways downstream of KRAS . . .
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