The genomic landscape of cholangiocarcinoma reveals the disruption of post-transcriptional modifiers

HIGHLIGHTS

• who: Yaodong Zhang from the Medical University have published the article: The genomic landscape of cholangiocarcinoma reveals the disruption of post-transcriptional modifiers, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors included genomic data from 348 CCA samples (including 87 from pCCA and 261 from iCCA) to investigate the genomic landscapes of both pCCA and iCCA. Although the authors provide evidence to demonstrated that METTL14-mediated m6A modification repressed the MACF1/u03b2catenin pathway in CCA, while METTL14R298H mutation | https://doi.org/10.1038/s41467-022-30708-7 disrupted this mechanism, m6A-related key . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.