Crispr-cas12a induced dna double-strand breaks are repaired by multiple pathways with different mutation profiles in magnaporthe oryzae

HIGHLIGHTS

• who: Jun Huang from the Department of Plant Pathology, Kansas State University, Manhattan, KS, USA have published the Article: CRISPR-Cas12a induced DNA double-strand breaks are repaired by multiple pathways with different mutation profiles in Magnaporthe oryzae, in the Journal: (JOURNAL)
• what: Through Ku80 deletion analysis, a key protein required for canonical non-homologous end joining, the authors demonstrate activity of an alternative end joining mechanism that creates larger DNA deletions, and uses longer microhomology compared to C-NHEJ.
• how: Given that more than half of the identified buff mutants across the . . .
  

   

  

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