Novel 3-aminobenzofuran derivatives as multifunctional agents for the treatment of alzheimer s disease

HIGHLIGHTS

  • who: . and colleagues from the University of Pisa, Italy have published the article: Novel 3-aminobenzofuran derivatives as multifunctional agents for the treatment of Alzheimer s disease, in the Journal: (JOURNAL)
  • how: The authors used the thioflavin T (ThT) assay. The obtained results showed that the tested 3-aminobenzofuran compounds (5a 5f 5h 5i and 5l) at 10 u03bcM concentration exhibited good inhibitory activity of self-induced Au03b21-42 aggregation (17.6% 29.8% 38.8% 24.8% and 25.7% inhibition respectively) compared to donepezil as the reference drug (14.9%). The obtained results . . .

     

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