The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease

HIGHLIGHTS

  • who: Colin T. Shearn and colleagues from the Pathology, School of Medicine, of Colorado Anschutz Medical Campus, Aurora, CO, United States have published the paper: The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease, in the Journal: PLOS ONE of 17/Oct/2022
  • what: The aim of this study was to examine interactions between oxidative stress and autophagy in cholestasis. The authors examined the impact of cholestasis on expression of Nrf2-dependent antioxidant genes and induction of autophagy. For the first time, the authors show that the . . .

     

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