Preclinical investigation of artesunate as a therapeutic agent for hepatocellular carcinoma via impairment of glucosylceramidase-mediated autophagic degradation

HIGHLIGHTS

• who: Wenjia Chen from the (UNIVERSITY) have published the research work: Preclinical investigation of artesunate as a therapeutic agent for hepatocellular carcinoma via impairment of glucosylceramidase-mediated autophagic degradation, in the Journal: (JOURNAL) of 20/09/2022
• what: The authors first observed GBA mRNA and protein overexpression in human HCC tissues compared with paired adjacent noncancerous liver tissues, and this finding was supported by the data obtained from analysis based on the TCGA database and by the in_vitro and in_vivo experimental data.
• how: The microarray data in Fig 1a show that the level . . .
  

   

  

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