Dissecting intra-tumoral changes following immune checkpoint blockades in intrahepatic cholangiocarcinoma via single-cell analysis

HIGHLIGHTS

  • who: Bao-Ye Sun and colleagues from the Department Liver Surgery and Transplantation, Liver Institute, Zhongshan Hospital, and Key Laboratory and (Ministry, Fudan University, Shanghai, China have published the research work: Dissecting Intra-Tumoral Changes Following Immune Checkpoint Blockades in Intrahepatic Cholangiocarcinoma via Single-Cell Analysis, in the Journal: (JOURNAL) of December/31,/2020
  • what: The authors assessed the intra-tumoral changes in ICC patients receiving ICBs via a publicly available single-cell dataset mining.

SUMMARY

    After normalization and principal component analysis (PCA) on the highly variable genes (k=2400), the . . .

     

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