Therapeutic non-invasive brain treatments in alzheimer’s disease: recent advances and challenges

HIGHLIGHTS

• who: Chongyun Wu from the brain clearance pathways in an AD animal model [171, ]Mild cognitive impairment (MCI) is one of the typical symptoms of AD [176]. In a scopolamine-induced ADrelated MCI mouse model, both the low- and high-frequency rTMS (, Hz and , Hz) were applied to the head of the rats for two sessions. AD mouse with rTMS treatment showed significantly improved cognitive function in a frequency-dependent manner, with the high-frequency rTMS exhibiting better improvement effects on cognitive function [176]. Similar results were found in the Au03b2, administration-induced AD mouse model [177 . . .
  

   

  

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