Tdp43 promotes stemness of breast cancer stem cells through cd44 variant splicing isoforms

HIGHLIGHTS

• who: Lu Guo from the (UNIVERSITY) have published the paper: TDP43 promotes stemness of breast cancer stem cells through CD44 variant splicing isoforms, in the Journal: (JOURNAL) of 29/09/2021
• what: In this study, TDP43 was identified as an important factor participating in the maintenance of BCSC stemness by increasing CD44v inclusion, especially CD44v8-10. Increasing evidence, including the research , shows that CD44, which is the most common CSC marker, contains various isoforms, and CD44 AS may not be controlled by a single splicing factor or regulatory mode.
• how: Showed that the . . .
  

   

  

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