Two phenotypes of chronic recurrent multifocal osteomyelitis with different patterns of bone involvement

HIGHLIGHTS

• who: Dita Cebecauerovu00e1 from the Chronic Recurrent Multifocal Osteomyelitis (CRMO) is an autoinflammatory bone disorder with predominantly paediatric onsetChildren present with multifocal osteolytic lesions accompanied by bone pain and soft tissue swelling. Patients often exhibit extraosseous co-morbidities such as psoriasis, inflammatory bowel disease, and arthritis. Objectives: Comparison of children with two different phenotypes of CRMO defined by presence or absence of extraosseous co-morbidities. Methods: Children diagnosed with CRMO at the Motol University Hospital between , and , were retrospectively reviewed, and according to the absence or presence of extraosseous manifestations divided into two cohorts, bone limited CRMO . . .
  

   

  

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