Novel interaction interfaces mediate the interaction between the neil1 dna glycosylase and mitochondrial transcription factor a

HIGHLIGHTS

  • who: (TFAM and colleagues from the University of North Carolina at Charlotte, United States have published the paper: Novel interaction interfaces mediate the interaction between the NEIL1 DNA glycosylase and mitochondrial transcription factor A, in the Journal: (JOURNAL)
  • what: In one scenario, when TFAM, NEIL1, and DNA are combined in a 1:1:1 M ratio, the authors propose that both NEIL1 and TFAM can individually bind to half of the available DNA, leaving some amount of protein unbound.
  • how: Even though complex formation between NEIL1 and TFAM is favored at lower salt . . .

     

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