Tdp1-independent pathways in the process and repair of top1-induced dna damage

HIGHLIGHTS

• who: Huimin Zhang from the The University have published the research: TDP1-independent pathways in the process and repair of TOP1-induced DNA damage, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors investigated the mechanisms underlying the repair of TOP1-induced DNA damage, with or without TDP1.
• how: After deep sequencing and obtaining sgRNA counts in each sample (Supplementary Data 1 and 2) the authors used a drug Z analysis to compare the CPT-treated group with the NT group in WT or TDP1-KO cells to determine CPT sensitivity profiling . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.