Arhgef37 overexpression promotes extravasation and metastasis of hepatocellular carcinoma via directly activating cdc42

HIGHLIGHTS

  • who: Xin Zhang from the Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China have published the research work: ARHGEF37 overexpression promotes extravasation and metastasis of hepatocellular carcinoma via directly activating Cdc42, in the Journal: (JOURNAL)
  • what: The authors focused on ARHGEF37 for further investigation. During the treatment course, ZCL278-treated mice did not exhibit obvious weight loss, diarrhea, anorexia, skin ulceration and general non-well-being, as well as alterations of the alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels, compared with the vehicle-treated mice, which indicated that the . . .

     

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