How organ-on-a-chip technology can assist in studying the role of the glymphatic system in neurodegenerative diseases

HIGHLIGHTS

• who: Sarah Spitz and collaborators from the Faculty of Technical Chemistry, Vienna University of Technology, Getreidemarkt, Vienna, Austria have published the research: How Organ-on-a-Chip Technology Can Assist in Studying the Role of the Glymphatic System in Neurodegenerative Diseases, in the Journal: (JOURNAL)
• what: The study showed not only that fluidic drainage was AQP4-dependent but also that the inhibition of the latter in_vitro resulted in impaired fluid clearance. The study provides a perfect practical example of how microfluidics can be employed to investigate the glymphatic system ex vivo.
• future: The . . .
  

   

  

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