Cell-based therapies have disease-modifying effects on osteoarthritis in animal models. a systematic review by the esska orthobiologic initiative. part 1: adipose tissue-derived cell-based injectable therapies

HIGHLIGHTS

SUMMARY

The aim of this systematic review was to investigate in preclinical studies the presence of diseasemodifying effects driven by cell-based products used for the injective treatment of OA. While additional publications by this group (The ESSKA Orthobiologic Initiative=ORBIT) will investigate other MSC sources, this article will focus on the effects of adipose_tissue derived products. OR microfra* adipose_tissue OR stromal vascular fraction OR SVF OR amniotic suspension allograft OR ASA OR placenta* OR umbilical cord OR amnio*) AND_(osteoarthritis). The OA model was surgically induced in 44 studies (mostly Disease‑modifying effects on . . .

 



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