HIGHLIGHTS
- who: Jia Wei from the Nanjing Medical University, China have published the research: The role of the macrophage-to-myofibroblast transition in renal fibrosis, in the Journal: (JOURNAL)
- how: The results found that more than 90% of monocytes/ macrophages in the injured kidney came from bone marrow while a-SMA was expressed in 22% of BMDMs accounting for almost 80% of all a-SMA+ myofibroblasts in the injured kidney. The results indicated that collagen-producing MMT_cells accounted for an important component of the myofibroblast population in renal allograft injury and contribute to the development of . . .
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