Heterogeneity and transcriptome changes of human cd8+ t cells across nine decades of life

HIGHLIGHTS

• who: Jian Lu from the (UNIVERSITY) have published the research work: Heterogeneity and transcriptome changes of human CD8+ T cells across nine decades of life, in the Journal: (JOURNAL) of 15/01/2022
• what: The authors develop a machine_learning model capable of predicting the age of individual cells based on their transcriptomic features, which are closely associated with their differentiation and mutation burden.
• how: The authors investigated if ML models could use singlecell transcriptome data to report a biological age for a single cell that correlated with the chronological age of its donor . . .
  

   

  

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