HIGHLIGHTS
SUMMARY
Such voluntary behaviors are driven by intrinsic motivation and are critical for the development and optimization of cognitive, social, and physical functions throughout life (Parisi et_al, 2019; Ryan and Deci, 2000). In mammals, dopamine signaling is modulated by endocannabinoids (El Khoury et_al, 2012; Wenzel and Cheer, 2018) and they play a critical role in motivation for voluntary behaviors, such as social play and physical exercise (Muguruza et_al, 2019; Parsons and Hurd, 2015; Vanderschuren et_al, 2016). The doses were selected based on previous studies (Achterberg et_al, 2016; Gilbert and Soderstrom, 2013; Muguruza et_al, 2019; Trezza . . .
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