Ex vivo expanded human regulatory t cells modify neuroinflammation in a preclinical model of alzheimer’s disease

HIGHLIGHTS

  • who: Alireza Faridar from the Institute, Fannin Street, Suite STu2011802, Houston, TX, USA have published the Article: Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimeru2019s disease, in the Journal: (JOURNAL)
  • what: Based on the data obtained from similar studies in infusing Treg into preclinical mice model , and considering temporal expression profile of CNS inflammatory genes in 5xFAD mice , this study was designed to administer 1 u00d7 u00ad106 ex vivo expanded Tregs, suspended in a 200 u03bcl of phosphate-buffered saline (PBS), into 5-month-old 5xFAD-Rag2KO and . . .

     

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