Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity

HIGHLIGHTS

  • who: Marcos A. Perez and collaborators from the School of Molecular Biosciences and Center for Reproductive Biology Washington State University have published the paper: Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity, in the Journal: (JOURNAL) of September/30,/2022
  • what: Instead the authors demonstrate that homeostasis in C. elegans leading to altered ratios of saturated and monounsaturated fatty acid (MUFA) content in cellular membranes. The authors demonstrate that ferroptosis sensitivity in both wild type and deficient mutants can be rescued in several ways that change the relative abundance of saturated fats MUFAs . . .

     

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