G2019s lrrk2 mutation enhances mpp+-induced inflammation of human induced pluripotent stem cells-differentiated dopaminergic neurons

HIGHLIGHTS

  • who: Chun-Feng Liu and Hong-Zhe Bei from the Soochow, China have published the article: G2019S LRRK2 Mutation Enhances MPP+-Induced Inflammation of Human Induced Pluripotent Stem Cells-Differentiated Dopaminergic Neurons, in the Journal: (JOURNAL)
  • what: A dose-dependent study was conducted to assess the effect of MPP+ on the death of DA neurons. Although the majority of PD cases are idiopathic, the effects of mutations associated with familial PD, such as SNCA, LRRK2, PARK2, PINK1, and GBA remain the focus of current research (Zhang et_al, 2021).
  • future: Work is needed to . . .

     

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