HIGHLIGHTS
- who: Physiological Reports. and collaborators from the , have published the article: Disparate biomechanical properties of the aorta in nonu2010aneurysmal and aneurysmal mice treated with angiotensin II, in the Journal: (JOURNAL)
- what: This study describes pronounced endothelial dysfunction in AngII-u00adtreated mice, including reduced sensitivity (IC50) to ACh-u00adinduced NO production and decreased production of basal NO, without altered sensitivity of VSMC to exogenous NO donor DEANO.
SUMMARY
Arterial stiffness has gained much recognition as a hallmark and independent predictor of cardiovascular disease (Laurent et_al, 2003; Mattace-Raso et_al, 2006; Willum-Hansen . . .
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