A single-molecule strategy to capture non-native intramolecular and intermolecular protein disulfide bridges

HIGHLIGHTS

  • who: Marc Mora and colleagues from the Stephanie Board, Department of Physics, Randall Centre for Cell and Molecular Biophysics and London Centre for Nanotechnology, King`s College London, WC R LS London, United Kingdom have published the Article: A Single-Molecule Strategy to Capture Non-native Intramolecular and Intermolecular Protein Disulfide Bridges, in the Journal: (JOURNAL) of May/12,/2022
  • what: The approach showcases the power of mechanical force as a conformational probe in dynamically evolving proteins and presents a platform to detect non-native disulfide bridges with singlemolecule resolution. Using a combination of protein . . .

     

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