Greener cleavage of protected peptide fragments from sieber amide resin

HIGHLIGHTS

  • who: Sieber Amide, Resin and The N-dealkylation, is a from the (UNIVERSITY) have published the Article: Greener Cleavage of Protected Peptide Fragments from Sieber Amide Resin, in the Journal: (JOURNAL)
  • what: Cleaving H H(Trt)L NH2 and H N(Trt)L NH2 peptides following the protocol in this study showed no evidence of Trt group removal with the greener alternates nor with DCM.
  • how: An optimisation for this new cleavage protocol was implemented to provide a complete 100 % cleavage yield.

SUMMARY

    Albericio`s group also has introduced . . .

     

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