Α-synuclein buildup is alleviated via escrt-dependent endosomal degradation brought about by p38mapk inhibition in cells expressing p25α

HIGHLIGHTS

• who: Helena Borland from the Helena Borland1, Izabela Rasmussen1, Kaare Bjerregaard-Andersen2, Michel Rasmussen1, Anders Olsen3, and Frederik Vilhardt1, * From the Department of Cellular and Molecular Medicine, The Faculty of Health Sciences, The Panum Institute, University of Copenhagen, Copenhagen, Denmark have published the Article: u03b1-synuclein buildup is alleviated via ESCRT-dependent endosomal degradation brought about by p38MAPK inhibition in cells expressing p25u03b1, in the Journal: (JOURNAL) of November/26,/2021
• what: The authors show here that p38MAPK inhibition via a degradative mechanism, that depends on the ESCRT machinery, lessens cytotoxicity and u03b1Syn secretion in . . .
  

   

  

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