HIGHLIGHTS
SUMMARY
Ferroptosis plays an essential role in regulating cancer development and can be used in antitumor treatment and predicting prognosis (Jiang et_al, 2021; Zhang et_al, 2022). The induction of ferroptosis becomes a candidate strategy for inducing tumor cell death, particularly in treating resistant cancers (Hassannia et_al, 2019; Lei et_al, 2022). Studies have shown that some genes, such as Aldh3a2 (Yusuf et_al, 2020), p53 (Birsen et_al, 2021), and GPX1 (Wei et_al, 2020), regulated ferroptosis in cancer cells and affected AML prognosis. The authors comprehensively analyzed the ARNTL expression and correlation with the prognosis of AML patients . . .
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