Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of ucp1 in skeletal muscle

HIGHLIGHTS

  • who: Jinit Masania from the Clinical Sciences Research Laboratories, Warwick Medical School, University of Warwick, University Hospital, Coventry, DX, UK have published the research work: Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle, in the Journal: (JOURNAL)
  • what: Aged HSA-mUCP1 mice had decreased MG-derived AGEs in skeletal muscle and decreased whole body MG-derived AGE exposure which is likely linked to the healthy aging phenotype.

SUMMARY

    Transcriptomic studies indicated increased expression of enzymes of amino_acid metabolism and antioxidant . . .

     

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