Ti ions induce il-1β release by activation of the nlrp3 inflammasome in a human macrophage cell line

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  • who: Mattias Pettersson from the (UNIVERSITY) have published the article: Ti Ions Induce IL-1u03b2 Release by Activation of the NLRP3 Inflammasome in a Human Macrophage Cell Line, in the Journal: (JOURNAL) of 11/02/2022
  • what: The aim of this study was to investigate whether titanium (Ti)-induced release of interleukin (IL)-1u03b2 acts through the assembly of the NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome. In the experiments with knockdown cells, only Ti-ion solution was used as the stimulation agent in the concentration range of 0-1000 u00b5M. In . . .

     

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