HIGHLIGHTS
- who: Posted Date October and colleagues from the Chongqing Medical University have published the paper: An ER-Horse Detonating Stress Cascade for Hepatocellular Carcinoma Nanotherapy, in the Journal: (JOURNAL)
- what: Inspired by these natural properties, herein, the authors report a hepatocellular carcinoma (HCC) cell-targeted ERV encapsulating siGRP94, denoted as ER-horse for the precise nanotheraoy. This work provides a novel and general strategy for construction of versatile ER membrane-based vesicles that can be used to trigger stress cascade with homologous targetability effects for therapy and may suit the needs of diverse biomedical applications . . .
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