HIGHLIGHTS
SUMMARY
Patients with cystic fibrosis (CF) often complain of joint manifestations., mostly episodic arthritis, pulmonary hypertrophic osteo-arthropathy (HPOA), antibiotic-induced pain and spinal pain. Many systemic diseases have been reported in association with CF, including rheumatoid arthritis (RA) and sarcoidosis. Only few studies have reported the association between CF and juvenile idiopathic arthritis (JIA) and addressed the therapeutic challenges of these patients. The authors describe the first pediatric case of a patient affected by CF, Basedow`s disease and JIA who was contemporarily treated with elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) CF transmembrane conductance . . .
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