Βhb inhibits glucose-induced glp-1 secretion in glutag and human jejunal enteroids

HIGHLIGHTS

  • who: u03b2-hydroxybutyrate et al. from the University of Gothenburg, Gothenburg, Sweden have published the research work: u03b2HB inhibits glucose-induced GLP-1 secretion in GLUTag and human jejunal enteroids, in the Journal: (JOURNAL)
  • what: The authors report that the ketone body u03b2HB significantly decreased GLP-1 secretion in murine EECs (GLUTag cells), which the authors also recently reported in primary mouse jejunal cell cultures (Wallenius et_al, 2020). This study also showed an increased expression of FFAR3 with stimulation of GLUTag cells with the ketone body u03b2HB. The authors demonstrate that the ketone body u03b2HB . . .

     

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