Mutual regulation between phosphofructokinase 1 platelet isoform and vegf promotes glioblastoma tumor growth

HIGHLIGHTS

• who: Je Sun Lim from the Cell culture U MG GBM cells were purchased from the Korean Cell Line Bank (KCLB have published the research work: Mutual regulation between phosphofructokinase 1 platelet isoform and VEGF promotes glioblastoma tumor growth, in the Journal: (JOURNAL) of 22/06/2022
• what: The authors demonstrate that PFKP promotes EGFR activation-induced VEGF expression in HIF-1u03b1-dependent and -independent manners in GBM cells, leading to enhanced blood vessel formation and brain tumor growth.
• how: Analyses of TCGA data showed that the expression levels of PFKP were positively . . .
  

   

  

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