Recapitulating infection, thermal sensitivity and antiviral treatment of seasonal coronaviruses in human airway organoids

HIGHLIGHTS

  • who: Pengfei Li from the Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, the Netherlands have published the research: Recapitulating infection, thermal sensitivity and antiviral treatment of seasonal coronaviruses in human airway organoids, in the Journal: (JOURNAL)
  • what: These features collectively bestow hAOs unique advantages to model a multitude of pulmonary diseases, especially respiratory infections such as Influenza and SARS-CoV-2.12-14 Given the overall lacking of knowledge and experimental models for studying seasonal HCoVs, this study aims to first establish hAOs-based 229E, OC43 and NL63 infection models. Using . . .

     

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