HIGHLIGHTS
- who: Seng Chuan Tang and colleagues from the Cancer Science Institute of, National University of, have published the article: Super-Enhancers, Phase-Separated Condensates, and 3D Genome Organization in Cancer, in the Journal: Cancers 2022, 2866 of /2022/
- future: More research is needed to understand what causes the difference between the nucleation of phase-separated condensates or transactivation hub at specific genomic loci to activate or silence genes. With improvements in the delivery of CRISPR/Cas9 and CRISPR/dCas9 vectors targeting oncogenic enhancer docking sites and super-anchors using these vectors could become potential future . . .
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