HIGHLIGHTS
- who: IGFBP and collaborators from the Department of Pharmacology, Sapporo Medical University School of Medicine, Sapporo, Japan have published the paper: Downregulation of contributes to replicative senescence via activation in mouse embryonic fibroblasts, in the Journal: (JOURNAL)
- what: The authors investigated the role of in replicative senescence in embryonic mouse fibroblasts (MEFs). The authors focused on the role of IGFBP5 in cellular senescence in MEFs. In the present study, Ezh2 mRNA level was reduced in P8 MEFs compared with that in P2 MEFs (Supplementary Figure 5A). In the present study, ERK2 was preferentially phosphorylated compared . . .
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